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---What’s the matter ________ your sister?
---She has a________ cold.
A.with; badB.on; badC.with; badlyD.on; badly
A

试题分析:句意:你的妹妹怎么了?她患了重感冒。What’s the matter with sb?……怎么了?用介词with,have a bad cold患重感冒,故选A。
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