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---_________ does he take this medicine?
---Twice a day.

A.How longB.How oftenC.How soonD.How much

B

解析试题分析:四个选项分别表示多长、多久一次、多久和多少钱。根据答语,一天两次。可知选B,他多久吃一次这种药?
考点:疑问词辨析
点评:英语中由how组合成德疑问词比较多,可以结合how的基本含义怎么,怎样来区分记忆。

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