I.RNAÊÇÉúÎïÌåÄÚ×îÖØÒªµÄÎïÖÊ»ù´¡Ö®Ò»£¬ËüÓëDNA¡¢µ°°×ÖÊÒ»Æð¹¹³ÉÁËÉúÃüµÄ¿ò¼Ü¡£µ«³¤ÆÚÒÔÀ´£¬¿Æѧ¼ÒÒ»Ö±ÈÏΪ£¬RNA½ö½öÊÇ´«µÝÒÅ´«ÐÅÏ¢µÄ¡°ÐÅʹ¡±¡£Ç°¼¸Ä꣬¿Æѧ¼ÒÃÇ·¢ÏÖ£¬ÆäÖÐһЩRNAСƬ¶ÎÄܹ»Ê¹Ìض¨µÄÖ²Îï»ùÒò´¦ÓڹرÕ״̬£¬ÕâÖÖÏÖÏó±»³Æ×÷¡°RNA¸ÉÈÅ¡±(RNAInterference¼ò³ÆRNAi)¡£½üÄ꣬·Ö×ÓÉúÎïѧ¼Ò·¢ÏÖRNAiÔÚÀÏÊóºÍÈËÌåϸ°ûÖÐÒ²¿ÉÒÔ¡°Í£Ö¹»ùÒò»î¶¯¡±¡£´ËÍ⣬ÉúÎïѧ¼Ò»¹·¢ÏÖÓйء°ÐÅʹRNA¡±(mRNA)Éú²ú¹ý³ÌµÄÐí¶àÐÂÐÅÏ¢£¬ÒÔ¼°RNAÓëµ°°×ÖʼäµÄ¹Øϵ¡£

¸ù¾ÝÉÏÊö²ÄÁϻشð£º

£¨1£©ÀÏÊóϸ°ûµÄϸ°ûºË¡¢             ¡¢             £¨Ìî¶þÖÖϸ°ûÆ÷£©µÈ½á¹¹ÖÐÓÐRNAµÄ·Ö²¼¡£

£¨2£©ÄãÈÏΪRNAʹÌض¨µÄ»ùÒò´¦ÓڹرÕ״̬£¬×î¿ÉÄÜÊÇÒÅ´«ÐÅÏ¢´«µÝµÄÄĸö¹ý³ÌÊÜ×裿 ²¢¼òÊöÀíÓÉ¡£                 

                                                                                                                                                                     

£¨3£©ÊÇ·ñ¿ÉÒÔ˵¡°RNAÒ²¿ÉÒÔ¿ØÖÆÉúÎïµÄÐÔ×´¡±£¿½áºÏÒÔÉϲÄÁÏ£¬ËµÃ÷ÀíÓÉ¡£ 

                                                                         

 II.ÏÂͼÊǽÍĸ¾úϸ°ûÄÚij»ùÒò¿ØÖÆϺϳɵÄmRNAʾÒâͼ¡£ÒÑÖªAUGΪÆðʼÃÜÂë×Ó£¬UAAΪÖÕÖ¹ÃÜÂë×Ó£¬¸ÃmRNA¿ØÖƺϳɵĶàëÄÁ´Îª¡°¼×Áò°±ËáÒ»ÁÁ°±Ëᡪ±½±û°±ËáÒ»±û°±ËáÒ»ÁÁ°±ËáÒ»ÁÁ°±ËáÒ»ÒìÁÁ°±ËáÒ»°ëë×°±Ëᡱ¡£

(4)ºÏ³ÉÉÏÊö¶àëÄÁ´Ê±,תÔËÁÁ°±ËáµÄtRNAÓÐ______ÖÖ¡£

(5) ÔÚת¼¹ý³ÌÖУ¬ÓÉÓÚijÖÖÔ­Òòµ¼Ö¸ÃmRNAÖÐÒ»¸ö¼î»ù(ͼÖд¦)ȱʧ£¬Ôò¼î»ùȱʧºóµÄmRNA¿ØÖƺϳɵĶàëÄÁ´µÄ°±»ùËáÐòÁÐÊÇ_________________________________________¡£

(6) ¸Ã»ùÒòµÄ¼î»ùÊýÔ¶´óÓÚ¸ÃmRNAµÄ¼î»ùÊýµÄÁ½±¶£¬ÆäÔ­ÒòÊÇ_____           _¡£

£¨1£©¡¢ÏßÁ£Ìå¡¢ºËÌÇÌå

£¨2£©¡¢ ת¼¡£·­ÒëÒ»°ã²»¾ßÓÐÌØÒìÐÔ£¬Ö»ÒªÓÐÁËÐÅʹRNA¡¢ºËÌÇÌ塢תÔËRNA¼°ÓÎÀëµÄ°±»ùËá¼°ÄÜÁ¿¡¢Ã¸µÈÌõ¼þ¾Í¿ÉÒÔ½øÐС£Èç¹û·­ÒëÊÜ×裬ÄǹرյĽ«²»ÊÇÌض¨µÄ»ùÒò£¬¶øÊÇËùÓеĻùÒò¶¼½«¹Ø±Õ

 £¨3£©¡¢¿ÉÒÔ˵Ã÷¡£ÒòΪRNA¿ÉÒÔ¸ÉÈÅDNA¹¦ÄÜ£¬Ê¹Ö®²»ÄÜ¿ØÖƵ°°×Öʵĺϳɣ¬´Ó¶ø¿ÉÒÔ¿ØÖÆÉúÎïÐÔ×´£»»òijЩRNA²¡¶¾¿ÉÒÔͨ¹ýÄæת¼À´ºÏ³ÉDNA£¬´Ó¶ø¿ØÖÆÉúÎïµÄÐÔ×´¡£

£¨4£©¡¢2ÖÖ    

£¨5£©¡¢¼×Áò°±ËáÒ»ÁÁ°±Ëᡪ±½±û°±ËáÒ»±û°±ËáÒ»°ëë×°±Ëᡱ

£¨6£©¡¢»ùÒò½á¹¹Öк¬Óв»±àÂëµ°°×ÖʵķDZàÂëÇøºÍÄÚº¬×ÓÇø¶Î

Á·Ï°²áϵÁдð°¸
Ïà¹ØÏ°Ìâ

¿ÆÄ¿£º¸ßÖÐÉúÎï À´Ô´£º2012½ìºþÄÏÊ¡ºâÑô°ËÖиßÈýµÚËÄ´ÎÔ¿¼ÉúÎïÊÔ¾í ÌâÐÍ£º×ÛºÏÌâ

I.RNAÊÇÉúÎïÌåÄÚ×îÖØÒªµÄÎïÖÊ»ù´¡Ö®Ò»£¬ËüÓëDNA¡¢µ°°×ÖÊÒ»Æð¹¹³ÉÁËÉúÃüµÄ¿ò¼Ü¡£µ«³¤ÆÚÒÔÀ´£¬¿Æѧ¼ÒÒ»Ö±ÈÏΪ£¬RNA½ö½öÊÇ´«µÝÒÅ´«ÐÅÏ¢µÄ¡°ÐÅʹ¡±¡£Ç°¼¸Ä꣬¿Æѧ¼ÒÃÇ·¢ÏÖ£¬ÆäÖÐһЩRNAСƬ¶ÎÄܹ»Ê¹Ìض¨µÄÖ²Îï»ùÒò´¦ÓڹرÕ״̬£¬ÕâÖÖÏÖÏó±»³Æ×÷¡°RNA¸ÉÈÅ¡±(RNAInterference¼ò³ÆRNAi)¡£½üÄ꣬·Ö×ÓÉúÎïѧ¼Ò·¢ÏÖRNAiÔÚÀÏÊóºÍÈËÌåϸ°ûÖÐÒ²¿ÉÒÔ¡°Í£Ö¹»ùÒò»î¶¯¡±¡£´ËÍ⣬ÉúÎïѧ¼Ò»¹·¢ÏÖÓйء°ÐÅʹRNA¡±(mRNA)Éú²ú¹ý³ÌµÄÐí¶àÐÂÐÅÏ¢£¬ÒÔ¼°RNAÓëµ°°×ÖʼäµÄ¹Øϵ¡£
¸ù¾ÝÉÏÊö²ÄÁϻشð£º
£¨1£©ÀÏÊóϸ°ûµÄϸ°ûºË¡¢            ¡¢            £¨Ìî¶þÖÖϸ°ûÆ÷£©µÈ½á¹¹ÖÐÓÐRNAµÄ·Ö²¼¡£
£¨2£©ÄãÈÏΪRNAʹÌض¨µÄ»ùÒò´¦ÓڹرÕ״̬£¬×î¿ÉÄÜÊÇÒÅ´«ÐÅÏ¢´«µÝµÄÄĸö¹ý³ÌÊÜ×裿²¢¼òÊöÀíÓÉ¡£                                                                                                                                                                                     
£¨3£©ÊÇ·ñ¿ÉÒÔ˵¡°RNAÒ²¿ÉÒÔ¿ØÖÆÉúÎïµÄÐÔ×´¡±£¿½áºÏÒÔÉϲÄÁÏ£¬ËµÃ÷ÀíÓÉ¡£ 
                                                                         
II.ÏÂͼÊǽÍĸ¾úϸ°ûÄÚij»ùÒò¿ØÖÆϺϳɵÄmRNAʾÒâͼ¡£ÒÑÖªAUGΪÆðʼÃÜÂë×Ó£¬UAAΪÖÕÖ¹ÃÜÂë×Ó£¬¸ÃmRNA¿ØÖƺϳɵĶàëÄÁ´Îª¡°¼×Áò°±ËáÒ»ÁÁ°±Ëᡪ±½±û°±ËáÒ»±û°±ËáÒ»ÁÁ°±ËáÒ»ÁÁ°±ËáÒ»ÒìÁÁ°±ËáÒ»°ëë×°±Ëᡱ¡£

(4)ºÏ³ÉÉÏÊö¶àëÄÁ´Ê±,תÔËÁÁ°±ËáµÄtRNAÓÐ______ÖÖ¡£
(5) ÔÚת¼¹ý³ÌÖУ¬ÓÉÓÚijÖÖÔ­Òòµ¼Ö¸ÃmRNAÖÐÒ»¸ö¼î»ù(ͼÖд¦)ȱʧ£¬Ôò¼î»ùȱʧºóµÄmRNA¿ØÖƺϳɵĶàëÄÁ´µÄ°±»ùËáÐòÁÐÊÇ___________________________¡£
(6) ¸Ã»ùÒòµÄ¼î»ùÊýÔ¶´óÓÚ¸ÃmRNAµÄ¼î»ùÊýµÄÁ½±¶£¬ÆäÔ­ÒòÊÇ_____¡£

²é¿´´ð°¸ºÍ½âÎö>>

¿ÆÄ¿£º¸ßÖÐÉúÎï À´Ô´£º2011½ì¸ÊËà¡¢ºÓ±±¡¢Ð½®¡¢¹óÖݸßÈý¾©º£Ïļ¾´óÁª¿¼£¨Àí×Û£©ÉúÎﲿ·Ö ÌâÐÍ£º×ÛºÏÌâ

΢ÉúÎïÓëÈËÀàµÄ¹Øϵ¼«ÎªÃÜÇУ¬ËäÈ»ÓÐЩ΢ÉúÎïÄÜʹÈ˺Ͷ¯Ö²Îﻼ²¡£¬µ«¶àÊý΢ÉúÎï¶ÔÈËÀàÊÇÓÐÒæµÄ¡£»Ø´ðÏÂÁÐÓйØ΢ÉúÎïµÄ֪ʶ£º
I£®ÔÚÑо¿DNAÊÇÉúÎïµÄÖ÷ÒªÒÅ´«ÎïÖÊʱ£¬°¬¸¥ÀïºÍËûµÄͬÊÂÀûÓ÷ÎÑ×Ë«Çò¾ú½øÐÐÁËÌåÍâת»¯ÊµÑ飬ÔÚ½«ÌáÈ¡µÄSÐÍϸ¾úÎïÖÊÓëRÐÍϸ¾ú»ìºÏºóÅàÑøʱ£¬·¢ÏÖÖ»ÓмÓÈËDNA£¬RÐÍϸ°û²ÅÄܹ»×ª»¯ÎªSÐÍϸ¾ú£¬ÇëÎÊ£ºÈçºÎÀûÓÃÈâÑÛÖªµÀRÐÍϸ¾ú·¢ÉúÁËת»¯?                                                    ¡£
¢ò£®Âé·ç¸Ë¾úÄÜÇÖº¦ÈË£¬¿Éͨ¹ýƤ·ô½Ó´¥£¬»òÓÉ·ÉÄ­´«²¥£¬¼²²¡Ç±·üÆÚ³¤£¬·¢²¡Âý£¬²¡³Ì³¤£¬Èç²»½øÐÐÖÎÁÆ£¬ÍùÍù·¢Õ¹ÖÁ×îÖÕËÀÍö¡£µ±ÈËÌå¸ÐȾÂé·ç¸Ë¾úºóËù½øÐеÄÃâÒß¡°Ð§Ó¦½×¶Î"ÊÇ£¨   £©

A£®ÁÜ°ÍÒò×Ó¡ú°Ðϸ°ûB£®Ð§Ó¦Tϸ°û¡ú°Ðϸ°û
C£®Tϸ°û¡úЧӦTϸ°ûD£®Ð§Ó¦Bϸ°û¡ú¿¹Ìå
¢ó£®¹È°±ËáÊÇÉúÎïÌåÄÚÒ»ÖÖÖØÒªµÄÓлúС·Ö×Ó£¬¹È°±ËáÄÆÊÇËüµÄÄÆÑΣ¬ÊÇζ¾«µÈµ÷ζƷµÄÖ÷Òª³É·Ö£¬Ä¿Ç°ÎÒÃÇ¿ÉÒÔÀûÓÃ΢ÉúÎï·¢½ÍÉú²ú¹È°±Ëá¡£

£¨1£©³£ÓõĹȰ±ËáÉú²ú¾úÖÖ³ýÁ˹Ȱ±Ëá°ô×´¸Ë¾úÍ⣬»¹ÓлÆÉ«¶Ì¸Ë¾ú¡£ÕâЩ¾úÖÖÔÚ»ùÒò½á¹¹ÉϵÄÖ÷ÒªÌصãÊÇ                                  ¡£
£¨2£©Èç¹ûÔÚµ°°×Öʺϳɹý³ÌÖУ¬Ð¯´ø¹È°±ËáµÄתÔËRNAÈçÓÒͼËùʾ£¬ÄÇô¶ÔÓ¦»ùÒòµÄ¼î»ùÐòÁÐÊÇ                                        ¡£
£¨3£©Ä³³§µÄ·¢½ÍÒºÔø²»É÷±»ÊɾúÌåÎÛȾ£¬¾úȺ´óÁ¿ËÀÍö£¬µ«ÈËÃÇÈ´½ÄÐÒ´ÓÖлñµÃÁËÉÙÊý¿ÉµÖ¿¹ÊɾúÌåµÄоúÖÖ£¬ÕâÖÖÐÂÐÔ×´µÄ²úÉúÀ´Ô´ÓÚ                          ¡£   

²é¿´´ð°¸ºÍ½âÎö>>

¿ÆÄ¿£º¸ßÖÐÉúÎï À´Ô´£º2011-2012ѧÄêºþÄÏÊ¡¸ßÈýµÚËÄ´ÎÔ¿¼ÉúÎïÊÔ¾í ÌâÐÍ£º×ÛºÏÌâ

I.RNAÊÇÉúÎïÌåÄÚ×îÖØÒªµÄÎïÖÊ»ù´¡Ö®Ò»£¬ËüÓëDNA¡¢µ°°×ÖÊÒ»Æð¹¹³ÉÁËÉúÃüµÄ¿ò¼Ü¡£µ«³¤ÆÚÒÔÀ´£¬¿Æѧ¼ÒÒ»Ö±ÈÏΪ£¬RNA½ö½öÊÇ´«µÝÒÅ´«ÐÅÏ¢µÄ¡°ÐÅʹ¡±¡£Ç°¼¸Ä꣬¿Æѧ¼ÒÃÇ·¢ÏÖ£¬ÆäÖÐһЩRNAСƬ¶ÎÄܹ»Ê¹Ìض¨µÄÖ²Îï»ùÒò´¦ÓڹرÕ״̬£¬ÕâÖÖÏÖÏó±»³Æ×÷¡°RNA¸ÉÈÅ¡±(RNAInterference¼ò³ÆRNAi)¡£½üÄ꣬·Ö×ÓÉúÎïѧ¼Ò·¢ÏÖRNAiÔÚÀÏÊóºÍÈËÌåϸ°ûÖÐÒ²¿ÉÒÔ¡°Í£Ö¹»ùÒò»î¶¯¡±¡£´ËÍ⣬ÉúÎïѧ¼Ò»¹·¢ÏÖÓйء°ÐÅʹRNA¡±(mRNA)Éú²ú¹ý³ÌµÄÐí¶àÐÂÐÅÏ¢£¬ÒÔ¼°RNAÓëµ°°×ÖʼäµÄ¹Øϵ¡£

¸ù¾ÝÉÏÊö²ÄÁϻشð£º

£¨1£©ÀÏÊóϸ°ûµÄϸ°ûºË¡¢             ¡¢             £¨Ìî¶þÖÖϸ°ûÆ÷£©µÈ½á¹¹ÖÐÓÐRNAµÄ·Ö²¼¡£

£¨2£©ÄãÈÏΪRNAʹÌض¨µÄ»ùÒò´¦ÓڹرÕ״̬£¬×î¿ÉÄÜÊÇÒÅ´«ÐÅÏ¢´«µÝµÄÄĸö¹ý³ÌÊÜ×裿 ²¢¼òÊöÀíÓÉ¡£                                                                                                                                                                                      

£¨3£©ÊÇ·ñ¿ÉÒÔ˵¡°RNAÒ²¿ÉÒÔ¿ØÖÆÉúÎïµÄÐÔ×´¡±£¿½áºÏÒÔÉϲÄÁÏ£¬ËµÃ÷ÀíÓÉ¡£ 

                                                                         

 II.ÏÂͼÊǽÍĸ¾úϸ°ûÄÚij»ùÒò¿ØÖÆϺϳɵÄmRNAʾÒâͼ¡£ÒÑÖªAUGΪÆðʼÃÜÂë×Ó£¬UAAΪÖÕÖ¹ÃÜÂë×Ó£¬¸ÃmRNA¿ØÖƺϳɵĶàëÄÁ´Îª¡°¼×Áò°±ËáÒ»ÁÁ°±Ëᡪ±½±û°±ËáÒ»±û°±ËáÒ»ÁÁ°±ËáÒ»ÁÁ°±ËáÒ»ÒìÁÁ°±ËáÒ»°ëë×°±Ëᡱ¡£

(4)ºÏ³ÉÉÏÊö¶àëÄÁ´Ê±,תÔËÁÁ°±ËáµÄtRNAÓÐ______ÖÖ¡£

(5) ÔÚת¼¹ý³ÌÖУ¬ÓÉÓÚijÖÖÔ­Òòµ¼Ö¸ÃmRNAÖÐÒ»¸ö¼î»ù(ͼÖд¦)ȱʧ£¬Ôò¼î»ùȱʧºóµÄmRNA¿ØÖƺϳɵĶàëÄÁ´µÄ°±»ùËáÐòÁÐÊÇ_________________________________________¡£

(6) ¸Ã»ùÒòµÄ¼î»ùÊýÔ¶´óÓÚ¸ÃmRNAµÄ¼î»ùÊýµÄÁ½±¶£¬ÆäÔ­ÒòÊÇ_____¡£

 

²é¿´´ð°¸ºÍ½âÎö>>

¿ÆÄ¿£º¸ßÖÐÉúÎï À´Ô´£º ÌâÐÍ£ºÔĶÁÀí½â

I.RNAÊÇÉúÎïÌåÄÚ×îÖØÒªµÄÎïÖÊ»ù´¡Ö®Ò»£¬ËüÓëDNA¡¢µ°°×ÖÊÒ»Æð¹¹³ÉÁËÉúÃüµÄ¿ò¼Ü¡£µ«³¤ÆÚÒÔÀ´£¬¿Æѧ¼ÒÒ»Ö±ÈÏΪ£¬RNA½ö½öÊÇ´«µÝÒÅ´«ÐÅÏ¢µÄ¡°ÐÅʹ¡±¡£Ç°¼¸Ä꣬¿Æѧ¼ÒÃÇ·¢ÏÖ£¬ÆäÖÐһЩRNAСƬ¶ÎÄܹ»Ê¹Ìض¨µÄÖ²Îï»ùÒò´¦ÓڹرÕ״̬£¬ÕâÖÖÏÖÏó±»³Æ×÷¡°RNA¸ÉÈÅ¡±(RNAInterference¼ò³ÆRNAi)¡£½üÄ꣬·Ö×ÓÉúÎïѧ¼Ò·¢ÏÖRNAiÔÚÀÏÊóºÍÈËÌåϸ°ûÖÐÒ²¿ÉÒÔ¡°Í£Ö¹»ùÒò»î¶¯¡±¡£´ËÍ⣬ÉúÎïѧ¼Ò»¹·¢ÏÖÓйء°ÐÅʹRNA¡±(mRNA)Éú²ú¹ý³ÌµÄÐí¶àÐÂÐÅÏ¢£¬ÒÔ¼°RNAÓëµ°°×ÖʼäµÄ¹Øϵ¡£

¸ù¾ÝÉÏÊö²ÄÁϻشð£º

£¨1£©ÀÏÊóϸ°ûµÄϸ°ûºË¡¢             ¡¢             £¨Ìî¶þÖÖϸ°ûÆ÷£©µÈ½á¹¹ÖÐÓÐRNAµÄ·Ö²¼¡£

£¨2£©ÄãÈÏΪRNAʹÌض¨µÄ»ùÒò´¦ÓڹرÕ״̬£¬×î¿ÉÄÜÊÇÒÅ´«ÐÅÏ¢´«µÝµÄÄĸö¹ý³ÌÊÜ×裿 ²¢¼òÊöÀíÓÉ¡£                 

                                                                                                                                                                     

£¨3£©ÊÇ·ñ¿ÉÒÔ˵¡°RNAÒ²¿ÉÒÔ¿ØÖÆÉúÎïµÄÐÔ×´¡±£¿½áºÏÒÔÉϲÄÁÏ£¬ËµÃ÷ÀíÓÉ¡£ 

                                                                         

 II.ÏÂͼÊǽÍĸ¾úϸ°ûÄÚij»ùÒò¿ØÖÆϺϳɵÄmRNAʾÒâͼ¡£ÒÑÖªAUGΪÆðʼÃÜÂë×Ó£¬UAAΪÖÕÖ¹ÃÜÂë×Ó£¬¸ÃmRNA¿ØÖƺϳɵĶàëÄÁ´Îª¡°¼×Áò°±ËáÒ»ÁÁ°±Ëᡪ±½±û°±ËáÒ»±û°±ËáÒ»ÁÁ°±ËáÒ»ÁÁ°±ËáÒ»ÒìÁÁ°±ËáÒ»°ëë×°±Ëᡱ¡£

(4)ºÏ³ÉÉÏÊö¶àëÄÁ´Ê±,תÔËÁÁ°±ËáµÄtRNAÓÐ______ÖÖ¡£

(5) ÔÚת¼¹ý³ÌÖУ¬ÓÉÓÚijÖÖÔ­Òòµ¼Ö¸ÃmRNAÖÐÒ»¸ö¼î»ù(ͼÖд¦)ȱʧ£¬Ôò¼î»ùȱʧºóµÄmRNA¿ØÖƺϳɵĶàëÄÁ´µÄ°±»ùËáÐòÁÐÊÇ_________________________________________¡£

(6) ¸Ã»ùÒòµÄ¼î»ùÊýÔ¶´óÓÚ¸ÃmRNAµÄ¼î»ùÊýµÄÁ½±¶£¬ÆäÔ­ÒòÊÇ_____           _¡£

²é¿´´ð°¸ºÍ½âÎö>>

ͬ²½Á·Ï°²á´ð°¸