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  ____fire, all exits must be kept clear. 

   A. In place of   B. Instead of   C. In case of   D. In spite of 

C


解析:

in case of意为“以防万一”,根据其宾语fire可判断出“为了防止火灾,一切出口都要清除干净”。in place of 意为“代替”。instead of 意为“代替,而不是……”。in spite of 意为“不管”。

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