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    It is uncertain____side effect the medicine will bring about，although about two thousand patients have taken it.
    A．thatB．whatC．howD．whether
    B
    B【命题立意】考查主语从句的引导词。
    【解题思路】句意为：尽管大约有两千名病人服用过这种药物，但是，它会带来什么样的副作用还不确定。side effect 意为“副作用”，还原主语从句中的主干是the medicine will bring about  side effect。故选择what，what在本题中形容词，意为“什么样的”，起修饰作用。
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