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He has been talented at designing and creating things ________ he was young.

A.whenB.beforeC.sinceD.while

C

解析试题分析:考查连词:A. when当…时候,B. before在…前面,C. since自从,D. while虽然,句意:从小时候他一直很擅长设计和创造东西。因为和现在完成时连用,用since引导时间状语从句,选C。
考点:考查连词

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