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The pen ________ he is writing is mine.
A.with whichB.in which
C.on whichD.by which
with which是“介词+关系代词”结构,常用来引导定语从句。with有“用”的意思,介词之后只能用which,不能用that,with which在定语从句中作状语,即he is writing with a pen。
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