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____is well-known to all, the great changes have taken place in China.
A.ItB.thatC.AsD.Which
C
考查定语从句。此处有逗号隔开,此句子不是形式主语的句式,前面的句子修饰后面的句子构成一个非限制性定语从句,as可以放于句首,意思“这一点”来指代后句。
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