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Hemophilia(血友病)results when a gene fails to produce the protein needed for the blood to clot, or change from a liquid to a solidThe fault gene is passed from parents to childrenPeople with hemophilia suffer uncontrollable bleedingThis can result in paintissue swelling(肿胀)and permanent damage to joints and muscles

 One in every ten thousand males has the most common kind of hemophiliaIt's extremely rare for females to have itPatients can be treated with the missing clotting substanceThey generally can lead normal lives

  Scientists say gene treatment may be a possible way to cure hemophilia in the futureResearchers consider hemophilia the best disease for gene treatment because it is caused by a single fault geneAlso, only a small increase in the missing clotting substance could provide good resultsThey tested gene treatment in six patients with severe hemophilia

  Firstthey removed skin ceils from the patients’ armsThe researchers grew the cells in the laboratory. They added copies of the needed gene taken from healthy people. Then they created hundreds of millions of genetically  changed cellsThey placed these cells into the patients’ stomachsAfter four monthsthe amount of blood clotting substance in the blood increased in four of the six patientsSome of the patients reported a decrease in bleeding problemsHoweverten months later, the clotting substance was no longer in the patients’ blood. It is not clear if the implanted cells died or the added genes stopped working

The researchers say the study showed that gene treatment is safe for people with the most common kind of hemophiliaBut others expressed concern about the treatment because the effects were only temporary.

1 Which of the following statements is NOT true about hemophilia?

AIt is caused by a fault gene and is passed from parents

BIt suffers uncontrolled bleeding

CPeople with hemophilia don't have any physical damage and can lead normal lives.

DIt doesn't succeed in making protein needed for blood to form into clots

2 People with hemophilia can live normally when       .

Athey are treated with the missing clotting substance

Bthey accept the scientists’ help

Cgood copies of gene are placed in their bodies

Dthey place some genetically changed cells into their stomachs

3. By carrying out the experimentscientists conclude that   

Athe effects of treatments are excellent and last long

Bgene treatment is a safe and possible way to treat hemophilia

Cpeople with hemophilia can recover completely with gene treatment

 Dhemophilia is a disease that can be treated easily

4. Which of the following can be the title of the passage?

AWhether people with hemophilia can live a normal life

BHow to control the bleeding for the patients

CHow the researchers remove skin cells from patients and place these cells into the patients

  DThe gene treatment to the hemophilia.

 

答案:C;A;B;D
解析:

1、归纳判断题。从文中内容可知,A、B、D三项关于这一疾病的描述都是正确的,只有c项不对,第一段说患者会有组织肿胀,关节和肌肉的永久损伤。

2、细节判断题。第二段谈到用基因疗法,给人体补充缺少的让血凝结的物质,病人可以过正常生活。

3、细节判断题。文中说科学家发现基因疗法是血友病的最好疗法。

4、主旨大意题。全文围绕血友病及基因疗法展开叙述,显然D项可以作为本文的标题。

 


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Hemophilia(血友病)results when a gene fails to produce the protein needed for the blood to clot, or change from a liquid to a solid. The fault gene is passed from parents to children. People with hemophilia suffer uncontrolled bleeding. This can result in pain, tissue swelling(肿胀)and permanent damage to joints and muscles.

One in every ten thousand males has the most common kind of hemophilia. It’s extremely rare for females to have it. Patients can be treated with the missing clotting substance. They generally can lead normal lives.

Scientists say gene treatment may be a possible way to cure hemophilia in the future. Researchers consider hemophilia the best disease for gene treatment because it is caused by a single fault gene. Also, only a small increase in the missing clotting substance could provide good results. They tested gene treatment in six patients with severe hemophilia.

First, they removed skin cells from the patients’ arms. The researchers grew the cells in the laboratory. They added copies of the needed gene taken from healthy people. Then they created hundreds of millions of genetically changed cells. They placed these cells into the patients’ stomachs. After four months, the amount of blood clotting substance in the blood increased in four of the six patients. Some of the patients reported a decrease in bleeding problems. However, ten months later, the clotting substance was no longer in the patients’ blood. It is not clear if the implanted cells died or the added genes stopped working.

The researchers say the study showed that gene treatment is safe for people with the most common kind of hemophilia. But others expressed concern about the treatment because the effects were only temporary.

1. Which of the following statements is NOT true about hemophilia?

A. It is caused by a fault gene and is passed from parents.

B. It suffers uncontrolled bleeding.

C. People with hemophilia don’t have any physical damage and can lead normal lives.

D. It doesn’t succeed in making protein needed for blood to form into clots.

2. People with hemophilia can live normally when______.

A. they are treated with the missing clotting substance

B. they accept the scientists’ help

C. good copies of gene are placed in their bodies

D. they place some genetically changed cells into their stomachs

3. By carrying out the experiment, scientists conclude that______.

A. the effects of treatments are excellent and last long

B. gene treatment is a safe and possible way to treat hemophilia

C. people with hemophilia can recover completely with gene treatment

D. hemophilia is a disease that can be treated easily

4. Which of the following can be the title of the passage?

A. Whether people with hemophilia can live a normal life

B. How to control the bleeding for the patients

C. How the researchers remove skin cells from patients and place these cells into the patients

D. The gene treatment to the hemophilia

 

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       An Austrian monk named Gregor Mendel first saw inherited patterns in pea plants.He experimented with pea plants in the 1860s.One of the things, or traits(特质), Mendel studied was what makes some pea plants tall and some short.He said that the traits must come from units of heredity passed from the parent plants.These units were later called genes.

       In the mid-1900s, scientists discovered that genes are made of DN                         A.In the 1970s, scientists learned how to change DNA with genetic engineering.Scientists also learned that problems with certain genes cause diseases.Muscular dystrophy, cystic fibrosis, and hemophilia are some genetic diseases-diseases caused by problems in genes.Today, scientists are looking for ways to cure genetic diseases by changing genes through a process called gene therapy.

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       A.DNA is a kind of gene.

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       B.Half people inherit all genes from their mother, others from their father.

       C.Genes decide the trees shapes, the cats’ fur color and our eyes’ color as well.

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       B.was interested in why plants were different

       C.first called the units of heredity from parents genes

       D.was the first who discovered genes

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