A new oral medication to treat patients in the early stages of multiple sclerosis(多发性硬化) has shown considerable promise in two clinical trials, researchers announced on Wednesday.

The medication is on track to become just the third oral drug available to M.S. patients, and potentially the safest and most effective, experts said. The second oral drug, called Aubagio, was approved just last week.

The new trials, published online in The New England Journal of Medicine, found that the drug BG-12, developed by Biogen Idec, reduced relapsing M.S rates(旧病复发率)in patients by about 50 percent. The drug also obviously reduced the frequency of new brain damage , and slowed the progression of disease compared with a placebo(安慰剂).

In the two clinical trials, called Define and Confirm, patients were divided into two groups at random, taking 240 milligrams of BG-12 either twice or three times a day. Patients in a third group took a placebo. The combined results showed that the drug reduced the relapse rate by about 50 percent.

Taking BG-12 twice a day reduced the number of newly enlarging brain damages by 71 percent to 99 percent. The Define trial found a statistically significant 38 percent reduction in the progression to disability. The most frequent side effects were a temporary flushing(脸红)and warm feeling and other symptoms including nausea, diarrhea, cramping and vomiting. Though both types of side effects were common, they tended to reduce after the first few weeks of use and were tolerated by most patients.

However, Interferons, the drugs most commonly used in relapsing M.S., reduce relapses by about 30 percent, and have not been shown to slow the progression of the disease and disability. The newly approved Aubagio also reduces relapses by about 30 percent, and it has the advantage of being an oral drug.

BG-12 is an anti-inflammatory that works by protecting nerves against injury. “The safety track record is well known and appears to be very strong,” said Dr. Robert Fox, lead author of one of the new studies and medical director of the Mellen Center for Multiple Sclerosis Treatment.

“It’s a bright day for M.S. patients, but there is a gray cloud in that we still don’t have anything for those with progressive M.S.,” he added.

63. Which of the following is NOT the function of BG-12? 

A. It can slow the progression to disability significantly.

B. It can reduce relapses rates in patients with relapsing M.S.

C. It can decrease the number of brain damages caused by M.S.

D. It can make patients excited and ensure patients have a warm feeling.

64. What can you infer from the underlined sentence in the last paragraph? 

A. BG-12 can relieve the pain from the patients suffering from M.S.

B. There is hope but still a long way to find a cure for progressive M.S.

C. Scientists can not invent medication for patients with progressive M.S.

D. Patients in the early stages of M.S will still suffer a lot in the future.

65. Which can be the best title for the text?

A. Advantages of BG-12               B. Good news for the patients

C. Comparisons between three drugs           D. A new oral medication for the early M.S.

For a girl who's interested in fashion, what would be the dream job? Being a model? Probably
no–-that's for a pencil thin who doesn't eat. One answer is, fashion stylist.
Girls can find it hard to ignore this attractiveness and the field is opening up to normal girls,
not only style or fashion design majors(某专业的学生). "It looked too high before, but now I
find it more approachable," said Xue Rui, 22, a Fudan University Chinese literature graduate who works as an assistant stylist at Hermès in Shanghai. "There is no certain principle in dressing up models, and you can try every way with your own distinct taste to make them pretty and attractive." Some professionals said that Xue's not mistaken.
The attractiveness of this work is not only in the wonderful clothes. Now it's a career with a bright future and pay packet. The income can allow you to buy expensive clothes and, with your name and photo appearing on pages, readers will remember your fashion tips.
A stylist at a fashion magazine can have some unique rights. You have a chance to contact famous persons and dress them up in a style you like. You need to cooperate with top photographers and select places around the world to take photos in. You might also be invited to fashion shows of top brands and can select some of the favorite clothes.
"You have to be ‘all-round’:from hair and make up to clothes, shoes, and accessories (配饰) to the event," said He Qing, 21, a junior in fashion design at the Beijing Institute of Fashion Technology. "You have to know everything, and handle several things at the same time. It's challenging. That's why I love it."
So, remember girls, you've been warned.
【小题1】 The underlined phrase “ pay packet” (paragraph 3)  means________.

On the high-speed train Avignon to Paris, my husband and I landed in the only remaining seats on the train, in the middle of a car, directly opposite a Frenchwoman of middle years. It was an extremely uncomfortable arrangement to be looking straight into the eyes of a stranger. My husband and I pulled out books. The woman produced a large makeup case and made up her face. Except for a lunch break, she continued this activity for the entire three-hour trip. Every once in a while she surveyed the car with a bright-eyed glance, but never once did she catch my eye. My husband and I could have been a blanket wall.

I was amused, but some people would have felt uncomfortable , even repulsed(厌恶的）.there is something about making up in public that calls up strong emotional reactions. Partly it’s a question of hygiene. And it’s a matter of degree. Making up --- a private act--- has a way of neglecting the presence of others. I was once seated at a party with a model-actress who immediately waved a silly brush and began dusting her face at the table, demonstrating that while she was next to me, she was not with me.

In fact, I am generally prohibited from making up in public, except when I am in the company of cosmetics moment. In a gathering more professional than social, I would do so.

Kathy Peiss, a history professor at the University of Massachusetts in Amherst says that nose-powdering in the office was an occasion for outrage in 1920’s and 30’s. Deploring the practice as a waste of company time, trade journals advises managers to discourage it among workers. Peiss theorizes that it was female’s making up in what has been an all-male field that disturb some gentlemen.

Peiss tells me that after the 30’s , pulling out a make-up case was no longer an issue. It became an accepted practice. I asked if she feels free to apply lipstick at a professional lunch herself. Sounding mildly shocked, she says she would save that for the privacy of her car afterward. Why? Because it would be “a gesture of inappropriate feminity(女性化）.” One guess is that most professional women feel this way. There is evidence of the popularity of the new lipsticks that remain in place all day without retouching.

1.According to the author, “My husband and I could have been a blanket wall.” (Line 6, Para.1) most probably means “________”.

A. We were treated with an expressionless face.????

B. We looked at the French woman expressionlessly

C. We used books as a wall to avoid the woman’s eyes

D. We were of no existence in the French woman’s eyes

2.In the author’s opinion, she _______.

A. allows public making up on certain occasions

B. feels comfortable when making up in public

C. only makes up on social occasions

D. makes up before any professional gatherings

3.According to Peiss, nose powdering in an office was criticized mainly for the reason that ____.

A. normal office work was disturbed??????

B. it discouraged women’s interest in career

C. make dominance was emphasized there??

D. it distracted make workers’ focus on work

4.Why do most professional women give up using lipsticks in public?

A. Because they are worried about being looked down upon

B. Because it emphasizes their female features in wrong situations

C. Because it implies women’s disadvantages in academic fields

D. Because they are ashamed to be seen making up in front of males/

5.It can be inferred that in a highly open society, the differences between men and women ______.

A. have attracted little attention??????

B. hinder the social development

C. are attractive topics in talk shows???

D. still call for great concern

For a girl who's interested in fashion, what would be the dream job? Being a model? Probably

no–-that's for a pencil thin who doesn't eat. One answer is, fashion stylist.

  Girls can find it hard to ignore this attractiveness and the field is opening up to normal girls,

not only style or fashion design majors(某专业的学生). "It looked too high before, but now I

find it more approachable," said Xue Rui, 22, a Fudan University Chinese literature graduate who works as an assistant stylist at Hermès in Shanghai. "There is no certain principle in dressing up models, and you can try every way with your own distinct taste to make them pretty and attractive." Some professionals said that Xue's not mistaken.

   The attractiveness of this work is not only in the wonderful clothes. Now it's a career with a bright future and pay packet. The income can allow you to buy expensive clothes and, with your name and photo appearing on pages, readers will remember your fashion tips.

A stylist at a fashion magazine can have some unique rights. You have a chance to contact famous persons and dress them up in a style you like. You need to cooperate with top photographers and select places around the world to take photos in. You might also be invited to fashion shows of top brands and can select some of the favorite clothes.

   "You have to be ‘all-round’:from hair and make up to clothes, shoes, and accessories (配饰) to the event," said He Qing, 21, a junior in fashion design at the Beijing Institute of Fashion Technology. "You have to know everything, and handle several things at the same time. It's challenging. That's why I love it."

So, remember girls, you've been warned.

1. The underlined phrase “ pay packet” (paragraph 3)  means________.

A. a large bag        B. a large amount of money      C. chances    D. choices

2.Which of the following statements is true according to the passage?

A. There are certain principles in dressing up models.

B. The only attractiveness of this work is in the wonderful clothes.

C. Only style or fashion design majors can work as a fashion stylist.

D. A stylist knows how to make a person beautiful, from head to toe。

3.What is the unique right a stylist at a fashion magazine can have?

A. You have a chance to contact celebrities and dress them up in a style you like.

B. You need to cooperate with top photographers and select places around the world to take photos in.

C. You might also be invited to fashion shows of top brands and can select some of the favorite clothes.

D. All of above

4. What will the author write in the 6^th paragraph?

   A. Top brands that fashion stylists like best.

   B. Various fashion shows

   C. Difficulties that fashion stylists may meet

   D. Other dream jobs