a．in spite of意思是“尽管，不管”，后接________词或________词，用法同despite。

b．in spite of引导让步状语，而though/although引导让步状语________。Despite/In spite of the fact＋that从句也可以表示让步意义。

c．as也可表示“尽管”，它是连词，要连接句子，as引导的从句多用________形式。

Strange as it may seem, I never really wanted to be rich．

Much as I sympathize with your difficulties, there is little I can do to help you．