解:
(1)546-398,
=546-400+2,
=146+2,
=148;
(2)457+199,
=457+200-1,
=657-1,
=656;
(3)2.2×101,
=2.2×(100+1),
=2.2×100+2.2×1,
=220+2.2,
=222.2;
(4)32×0.125×25,
=8×4×0.125×25,
=(8×0.125)×(4×25),
=1×100,
=100;
(5)5.4×99+5.4,
=5.4×(99+1),
=5.4×100,
=540;
(6)(

+

+

)×21,
=

×21+

×21+

×21,
=9+5+3,
=17;
(7)999×999+999,
=999×(999+1),
=999×1000,
=999000;
(8)18.7×101-18.7,
=18.7×(101-1),
=18.7×100,
=1870.
分析:546-398,457+199运用凑整法简算;
2.2×101先把101分解成100+1,再运用乘法分配律简算;
32×0.125×25把32分解成4×8再运用乘法结合律简算;
5.4×99+5.4运用乘法分配律简算;
(

+

+

)×21运用乘法分配律简算;
999×999+999运用乘法分配律简算;
18.7×101-18.7运用乘法分配律简算.
点评:完成本题要注意分析式中数据,运用合适的简便方法计算.